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In vivo restoration of laminin 5 β3 expression and function in junctional epidermolysis bullosa

The blistering disorder, lethal junctional epidermolysis bullosa (JEB), can result from mutations in the LAMB3 gene, which encodes laminin 5 β3 (β3). Appropriate expression of LAMβ3 in JEB skin tissue could potentially ameliorate the symptoms of the underlying disease. To explore the utility of this...

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Detalhes bibliográficos
Main Authors: Robbins, Paul B., Lin, Qun, Goodnough, Julia B., Tian, Hongsheng, Chen, Xinjian, Khavari, Paul A.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC33186/
https://ncbi.nlm.nih.gov/pubmed/11296269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.091484998
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