Multiple Skin Squamous Cell Carcinomas in Junctional Epidermolysis Bullosa Due to Altered Laminin-332 Function

Variably reduced expression of the basement membrane component laminin-332 (α3aβ3γ2) causes junctional epidermolysis bullosa generalized intermediate (JEB-GI), a skin fragility disorder with an increased susceptibility to squamous cell carcinoma (SCC) development in adulthood. Laminin-332 is highly...

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Enregistré dans:
Détails bibliographiques
Publié dans:Int J Mol Sci
Auteurs principaux: Fortugno, Paola, Condorelli, Angelo Giuseppe, Dellambra, Elena, Guerra, Liliana, Cianfarani, Francesca, Tinaburri, Lavinia, Proto, Vittoria, De Luca, Naomi, Passarelli, Francesca, Ricci, Francesca, Zambruno, Giovanna, Castiglia, Daniele
Format: Artigo
Langue:Inglês
Publié: MDPI 2020
Sujets:
Case Report
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7073068/
https://ncbi.nlm.nih.gov/pubmed/32093196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21041426
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