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Rat Ace allele variation determines susceptibility to AngII induced renal damage

INTRODUCTION: Ace b/l polymorphism in rat is associated to differential tissue ACE expression and activity, and susceptibility to renal damage. Same polymorphism was recently found in outbred Wistar rat strain with b allele accounting for higher renal ACE, and provided a model for studying RAAS resp...

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Detalhes bibliográficos
Main Authors: Kamilic, Jelena, Hamming, Inge, Lely, A. Titia, Korstanje, Ron, Schulze, Ute, Poppinga, Wilfred J., Turner, Anthony J., Clarke, Nicola E., van Goor, Harry, Navis, Gerjan J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3356861/
https://ncbi.nlm.nih.gov/pubmed/21788250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1470320311415886
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