Hepatitis C virus epitope exposure and neutralization by antibodies is affected by time and temperature

A recent study with flaviviruses suggested that structural dynamics of the virion impact antibody neutralization via exposure of ostensibly cryptic epitopes. To determine whether this holds true for the distantly related hepatitis C virus (HCV), whose neutralizing epitopes may be obscured by a glyca...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Sabo, Michelle C., Luca, Vincent C., Ray, Stuart C., Bukh, Jens, Fremont, Daved H., Diamond, Michael S.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2011
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3356770/
https://ncbi.nlm.nih.gov/pubmed/22078164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2011.10.023
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