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Modelling the Spatio-Temporal Cell Dynamics Reveals Novel Insights on Cell Differentiation and Proliferation in the Small Intestinal Crypt

We developed a slow structural relaxation model to describe cellular dynamics in the crypt of the mouse small intestine. Cells are arranged in a three dimensional spiral the size of which dynamically changes according to cell production demands of adjacent villi. Cell differentiation and proliferati...

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Detalhes bibliográficos
Main Authors: Pin, Carmen, Watson, Alastair J. M., Carding, Simon R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3356410/
https://ncbi.nlm.nih.gov/pubmed/22623982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037115
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