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A Comprehensive Model of the Spatio-Temporal Stem Cell and Tissue Organisation in the Intestinal Crypt

We introduce a novel dynamic model of stem cell and tissue organisation in murine intestinal crypts. Integrating the molecular, cellular and tissue level of description, this model links a broad spectrum of experimental observations encompassing spatially confined cell proliferation, directed cell m...

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Autori principali: Buske, Peter, Galle, Jörg, Barker, Nick, Aust, Gabriela, Clevers, Hans, Loeffler, Markus
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3017108/
https://ncbi.nlm.nih.gov/pubmed/21253562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1001045
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