Preclinical evaluation of injectable sirolimus formulated with polymeric nanoparticle for cancer therapy

Nanoparticles are useful delivery vehicles for promising drug candidates that face obstacles for clinical applicability. Sirolimus, an inhibitor of mammalian target of rapamycin has gained attention for targeted anticancer therapy, but its clinical application has been limited by its poor solubility...

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Detalhes bibliográficos
Main Authors: Woo, Ha Na, Chung, Hye Kyung, Ju, Eun Jin, Jung, Joohee, Kang, Hye-Won, Lee, Sa-Won, Seo, Min-Hyo, Lee, Jin Seong, Lee, Jung Shin, Park, Heon Joo, Song, Si Yeol, Jeong, Seong-Yun, Choi, Eun Kyung
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2012
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3356221/
https://ncbi.nlm.nih.gov/pubmed/22619555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S29480
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