Preclinical evaluation of injectable sirolimus formulated with polymeric nanoparticle for cancer therapy

Nanoparticles are useful delivery vehicles for promising drug candidates that face obstacles for clinical applicability. Sirolimus, an inhibitor of mammalian target of rapamycin has gained attention for targeted anticancer therapy, but its clinical application has been limited by its poor solubility...

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Bibliographic Details
Main Authors: Woo, Ha Na, Chung, Hye Kyung, Ju, Eun Jin, Jung, Joohee, Kang, Hye-Won, Lee, Sa-Won, Seo, Min-Hyo, Lee, Jin Seong, Lee, Jung Shin, Park, Heon Joo, Song, Si Yeol, Jeong, Seong-Yun, Choi, Eun Kyung
Format: Artigo
Language:Inglês
Published: Dove Medical Press 2012
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3356221/
https://ncbi.nlm.nih.gov/pubmed/22619555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S29480
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