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Enhancing cellular uptake of activable cell-penetrating peptide–doxorubicin conjugate by enzymatic cleavage

The use of activable cell-penetrating peptides (ACPPs) as molecular imaging probes is a promising new approach for the visualization of enzymes. The cell-penetrating function of a polycationic cell-penetrating peptide (CPP) is efficiently blocked by intramolecular electrostatic interactions with a p...

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Bibliografiske detaljer
Main Authors: Shi, Nian-Qiu, Gao, Wei, Xiang, Bai, Qi, Xian-Rong
Format: Artigo
Sprog:Inglês
Udgivet: Dove Medical Press 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3356196/
https://ncbi.nlm.nih.gov/pubmed/22619516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S30104
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