Evaluation of Activity and Combination Strategies with the Microtubule-Targeting Drug Sagopilone in Breast Cancer Cell Lines

Sagopilone, a fully synthetic epothilone, is a microtubule-stabilizing agent optimized for high in vitro and in vivo activity against a broad range of tumor models, including those resistant to paclitaxel and other systemic treatments. Sagopilone development is accompanied by translational research...

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Bibliografiska uppgifter
Huvudupphovsmän: Eschenbrenner, Julia, Winsel, Sebastian, Hammer, Stefanie, Sommer, Anette, Mittelstaedt, Kevin, Drosch, Michael, Klar, Ulrich, Sachse, Christoph, Hannus, Michael, Seidel, Monika, Weiss, Bertram, Merz, Claudia, Siemeister, Gerhard, Hoffmann, Jens
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Research Foundation 2011
Ämnen:
Oncology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3355879/
https://ncbi.nlm.nih.gov/pubmed/22649765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2011.00044
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