The decreased expression of Beclin-1 correlates with progression to esophageal adenocarcinoma: the role of deoxycholic acid

Beclin-1 has a central role in the regulation of autophagy. Barrett's esophagus (BE) is associated with a significantly increased risk for the development of esophageal adenocarcinoma (EAC). In the current study, we evaluated the role of Beclin-1 and autophagy in the EAC. Biopsies obtained from...

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Bibliographic Details
Main Authors: Roesly, Heather B., Khan, Mohammad R., Chen, Hwu Dau Rw, Hill, Kimberly A., Narendran, Nirushan, Watts, George S., Chen, Xiaoxin, Dvorak, Katerina
Format: Artigo
Language:Inglês
Published: American Physiological Society 2012
Subjects:
Cancer Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3355563/
https://ncbi.nlm.nih.gov/pubmed/22301112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00340.2011
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