The Na(+)/H(+) Exchanger Controls Deoxycholic Acid-Induced Apoptosis by a H(+)-Activated, Na(+)-Dependent Ionic Shift in Esophageal Cells

Apoptosis resistance is a hallmark of cancer cells. Typically, bile acids induce apoptosis. However during gastrointestinal (GI) tumorigenesis the cancer cells develop resistance to bile acid-induced cell death. To understand how bile acids induce apoptosis resistance we first need to identify the m...

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Detalhes bibliográficos
Main Authors: Goldman, Aaron, Chen, HwuDauRw, Khan, Mohammad R., Roesly, Heather, Hill, Kimberly A., Shahidullah, Mohammad, Mandal, Amritlal, Delamere, Nicholas A., Dvorak, Katerina
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3161789/
https://ncbi.nlm.nih.gov/pubmed/21887327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023835
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