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Autotaxin and Its Product Lysophosphatidic Acid Suppress Brown Adipose Differentiation and Promote Diet-Induced Obesity in Mice

Brown adipose tissue is a thermogenic organ that dissipates stored energy as heat to maintain body temperature. This process may also provide protection from development of diet-induced obesity. We report that the bioactive lipid mediator lysophosphatidic acid (LPA) markedly decreases differentiatio...

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Detalhes bibliográficos
Main Authors: Federico, Lorenzo, Ren, Hongmei, Mueller, Paul A., Wu, Tao, Liu, Shuying, Popovic, Jelena, Blalock, Eric M., Sunkara, Manjula, Ovaa, Huib, Albers, Harald M., Mills, Gordon B., Morris, Andrew J., Smyth, Susan S.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3355557/
https://ncbi.nlm.nih.gov/pubmed/22474126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2011-1229
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