On the interactions between mesenchymal stem cells and regulatory T cells for immunomodulation in transplantation

Experimental studies have established the use of mesenchymal stem cells (MSC) as a candidate immunosuppressive therapy. MSC exert their immunomodulatory function through the inhibition of CD4(+) and CD8(+) T cell proliferation. It is unknown whether MSC impair the immunosuppressive function of regul...

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Main Authors: Engela, Anja U., Baan, Carla C., Dor, Frank J. M. F., Weimar, Willem, Hoogduijn, Martin J.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Research Foundation 2012
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3355477/
https://ncbi.nlm.nih.gov/pubmed/22629256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2012.00126
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