Human adipose-tissue derived mesenchymal stem cells induce functional de-novo regulatory T cells with methylated FOXP3 gene DNA

Due to their immunomodulatory properties, mesenchymal stem cells (MSC) are interesting candidates for cellular therapy for autoimmune disorders, graft-versus-host disease and allograft rejection. MSC inhibit the proliferation of effector T cells and induce T cells with a regulatory phenotype. So far...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Engela, A U, Hoogduijn, M J, Boer, K, Litjens, N H R, Betjes, M G H, Weimar, W, Baan, C C
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Blackwell Science Inc 2013
Pynciau:
Original Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3722934/
https://ncbi.nlm.nih.gov/pubmed/23607314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.12120
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