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Prochelators Triggered by Hydrogen Peroxide Provide Hexadentate Iron Coordination to Impede Oxidative Stress

Prochelators are agents that have little affinity for metal ions until they undergo a chemical conversion. Three new aryl boronate prochelators are presented that are responsive to hydrogen peroxide to provide hexadentate ligands for chelating metal ions. TRENBSIM (tris[(2-(4,4,5,5-tetramethyl-1,3,2...

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Autors principals: Leed, Marina G. D., Wolkow, Natalie, Pham, David M., Daniel, Catherine L., Dunaief, Joshua L., Franz, Katherine J.
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3355344/
https://ncbi.nlm.nih.gov/pubmed/21708101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jinorgbio.2011.05.023
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