Single-nucleotide polymorphisms in the P2X7 receptor gene are associated with post-menopausal bone loss and vertebral fractures

The purinergic P2X7 receptor has a major role in the regulation of osteoblast and osteoclast activity and changes in receptor function may therefore affect bone mass in vivo. The aim of this study was to determine the association of non-synonymous single-nucleotide polymorphisms in the P2RX7 gene to...

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Detalhes bibliográficos
Main Authors: Jørgensen, Niklas R, Husted, Lise B, Skarratt, Kristen K, Stokes, Leanne, Tofteng, Charlotte L, Kvist, Torben, Jensen, Jens-Erik B, Eiken, Pia, Brixen, Kim, Fuller, Stephen, Clifton-Bligh, Rory, Gartland, Alison, Schwarz, Peter, Langdahl, Bente L, Wiley, James S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3355253/
https://ncbi.nlm.nih.gov/pubmed/22274585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2011.253
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