Network Topologies and Dynamics Leading to Endotoxin Tolerance and Priming in Innate Immune Cells

The innate immune system, acting as the first line of host defense, senses and adapts to foreign challenges through complex intracellular and intercellular signaling networks. Endotoxin tolerance and priming elicited by macrophages are classic examples of the complex adaptation of innate immune cell...

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Bibliographic Details
Main Authors: Fu, Yan, Glaros, Trevor, Zhu, Meng, Wang, Ping, Wu, Zhanghan, Tyson, John J., Li, Liwu, Xing, Jianhua
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3355072/
https://ncbi.nlm.nih.gov/pubmed/22615556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002526
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