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Molecular Mechanism Underlying Persistent Induction of LCN2 by Lipopolysaccharide in Kidney Fibroblasts

The neutrophil gelatinase-associated lipocalin 2 (LCN2) is a critical inflammatory mediator persistently induced during endotoxemia, contributing to tubular damage and kidney failure. The intracellular process responsible for persistent induction of LCN2 by bacterial endotoxin Lipopolysaccharide (LP...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Glaros, Trevor, Fu, Yan, Xing, Jianhua, Li, Liwu
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3326042/
https://ncbi.nlm.nih.gov/pubmed/22514649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0034633
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