Dietary L-arginine supplementation reduces Methotrexate-induced intestinal mucosal injury in rat

BACKGROUND: Arginine (ARG) and nitric oxide maintain the mucosal integrity of the intestine in various intestinal disorders. In the present study, we evaluated the effects of oral ARG supplementation on intestinal structural changes, enterocyte proliferation and apoptosis following methotrexate (MTX...

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Hauptverfasser: Koppelmann, Tal, Pollak, Yulia, Mogilner, Jorge, Bejar, Jacob, Coran, Arnold G, Sukhotnik, Igor
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2012
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3355056/
https://ncbi.nlm.nih.gov/pubmed/22545735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-230X-12-41
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