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The effect of mouse strain on herpes simplex virus type 1 (HSV-1) infection of the central nervous system (CNS)

BACKGROUND: Mice infected with HSV-1 can develop lethal encephalitis or virus induced CNS demyelination. Multiple factors affect outcome including route of infection, virus and mouse strain. When infected with a sub-lethal dose of HSV-1 strain 2 via the oral mucosa, susceptible SJL/J, A/J, and PL/J...

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Détails bibliographiques
Auteurs principaux: Kastrukoff, Lorne F, Lau, Allen S, Thomas, Eva E
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3355007/
https://ncbi.nlm.nih.gov/pubmed/22449238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2042-4280-3-4
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