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Stimulation of TLR4 by recombinant HSP70 requires structural integrity of the HSP70 protein itself
BACKGROUND: Toll-like receptor 4 (TLR4) is activated by bacterial endotoxin, a prototypical pathogen-associated molecular pattern (PAMP). It has been suggested that TLR4 can also be activated by damage-associated molecular pattern (DAMP) proteins such as HSP70. It remains a challenge to provide uneq...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BioMed Central
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3355006/ https://ncbi.nlm.nih.gov/pubmed/22448747 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-9255-9-11 |
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