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Interacting Alleles of the Coinhibitory Immunoreceptor Genes Cytotoxic T-Lymphocyte Antigen 4 and Programmed Cell-Death 1 Influence Risk and Features of Primary Biliary Cirrhosis

Autoimmune diseases such as primary biliary cirrhosis (PBC) result from failure in the immune mechanisms that establish and maintain self-tolerance. Evidence suggests that these processes are shared among the spectrum of autoimmune syndromes and are likely genetically determined. Cytotoxic T-lymphoc...

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Main Authors: Juran, Brian D., Atkinson, Elizabeth J., Schlicht, Erik M., Fridley, Brooke L., Petersen, Gloria M., Lazaridis, Konstantinos N.
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3354920/
https://ncbi.nlm.nih.gov/pubmed/18041714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.22048
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