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Early Minocycline Treatment Prevents a Decrease in Striatal Dopamine in an SIV Model of HIV-Associated Neurological Disease

HIV-infected individuals, even with antiretroviral therapy, often display cognitive, behavioral and motor abnormalities and have decreased dopamine (DA) levels. Minocycline prevents encephalitis and neurodegeneration in SIV models, suggesting that it might also protect against nigrostriatal dopamine...

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Main Authors: Meulendyke, Kelly A., Pletnikov, Mikhail V., Engle, Elizabeth L., Tarwater, Patrick M., Graham, David R., Zink, M. Christine
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3354017/
https://ncbi.nlm.nih.gov/pubmed/22198699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11481-011-9332-1
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