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Early Minocycline Treatment Prevents a Decrease in Striatal Dopamine in an SIV Model of HIV-Associated Neurological Disease

HIV-infected individuals, even with antiretroviral therapy, often display cognitive, behavioral and motor abnormalities and have decreased dopamine (DA) levels. Minocycline prevents encephalitis and neurodegeneration in SIV models, suggesting that it might also protect against nigrostriatal dopamine...

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Detalhes bibliográficos
Main Authors: Meulendyke, Kelly A., Pletnikov, Mikhail V., Engle, Elizabeth L., Tarwater, Patrick M., Graham, David R., Zink, M. Christine
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3354017/
https://ncbi.nlm.nih.gov/pubmed/22198699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11481-011-9332-1
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