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Angiotensin-(1–7) attenuates angiotensin II-induced cardiac remodeling associated with upregulation of dual-specificity phosphatase 1

Chronic hypertension induces cardiac remodeling, including left ventricular hypertrophy and fibrosis, through a combination of both hemodynamic and humoral factors. In previous studies, we showed that the heptapeptide ANG-(1–7) prevented mitogen-stimulated growth of cardiac myocytes in vitro, throug...

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Hlavní autoři: McCollum, LaTronya T., Gallagher, Patricia E., Ann Tallant, E.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3353789/
https://ncbi.nlm.nih.gov/pubmed/22140049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00908.2011
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