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Angiotensin-(1–7) attenuates angiotensin II-induced cardiac remodeling associated with upregulation of dual-specificity phosphatase 1

Chronic hypertension induces cardiac remodeling, including left ventricular hypertrophy and fibrosis, through a combination of both hemodynamic and humoral factors. In previous studies, we showed that the heptapeptide ANG-(1–7) prevented mitogen-stimulated growth of cardiac myocytes in vitro, throug...

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Detalhes bibliográficos
Main Authors: McCollum, LaTronya T., Gallagher, Patricia E., Ann Tallant, E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3353789/
https://ncbi.nlm.nih.gov/pubmed/22140049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00908.2011
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