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MAP kinase/phosphatase pathway mediates the regulation of ACE2 by angiotensin peptides
Angiotensin-converting enzyme 2 (ACE2) catalyzes the conversion of the vasoconstrictor angiotensin II (ANG II) to the vasodilatory peptide angiotensin-(1-7) [ANG-(1-7)]. We showed that treatment of hypertensive rats with the AT(1) receptor antagonist olmesartan increased ACE2 mRNA and protein in the...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2585001/ https://ncbi.nlm.nih.gov/pubmed/18768926 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00145.2008 |
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