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MAP kinase/phosphatase pathway mediates the regulation of ACE2 by angiotensin peptides

Angiotensin-converting enzyme 2 (ACE2) catalyzes the conversion of the vasoconstrictor angiotensin II (ANG II) to the vasodilatory peptide angiotensin-(1-7) [ANG-(1-7)]. We showed that treatment of hypertensive rats with the AT(1) receptor antagonist olmesartan increased ACE2 mRNA and protein in the...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Gallagher, Patricia E., Ferrario, Carlos M., Tallant, E. Ann
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Physiological Society 2008
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2585001/
https://ncbi.nlm.nih.gov/pubmed/18768926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00145.2008
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