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Activation of protein kinase C alters the intracellular distribution and mobility of cardiac Na(+) channels
Na(+) current derived from expression of the cardiac isoform SCN5A is reduced by receptor-mediated or direct activation of protein kinase C (PKC). Previous work has suggested a possible role for loss of Na(+) channels at the plasma membrane in this effect, but the results are controversial. In this...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Physiological Society
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3353784/ https://ncbi.nlm.nih.gov/pubmed/22101522 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00817.2010 |
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