BK channels regulate sinoatrial node firing rate and cardiac pacing in vivo

Large-conductance Ca(2+)- and voltage-activated K(+) (BK) channels play prominent roles in shaping muscle and neuronal excitability. In the cardiovascular system, BK channels promote vascular relaxation and protect against ischemic injury. Recently, inhibition of BK channels has been shown to lower...

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Main Authors: Lai, Michael H., Wu, Yuejin, Gao, Zhan, Anderson, Mark E., Dalziel, Julie E., Meredith, Andrea L.
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2014
Assuntos:
Cardiac Excitation and Contraction
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4217012/
https://ncbi.nlm.nih.gov/pubmed/25172903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00354.2014
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