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The cardiac L-type calcium channel distal carboxy terminus autoinhibition is regulated by calcium

The L-type calcium channel (LTCC) provides trigger Ca(2+) for sarcoplasmic reticulum Ca-release, and LTCC function is influenced by interacting proteins including the LTCC distal COOH terminus (DCT) and calmodulin. DCT is proteolytically cleaved and reassociates with the LTCC complex to regulate cal...

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Détails bibliographiques
Auteurs principaux: Crump, Shawn M., Andres, Douglas A., Sievert, Gail, Satin, Jonathan
Format: Artigo
Langue:Inglês
Publié: American Physiological Society 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3774502/
https://ncbi.nlm.nih.gov/pubmed/23203963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00396.2012
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