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Radiation/Paclitaxel Treatment of p53-Abnormal Non-Small Cell Lung Cancer Xenograft Tumor and Associated Mechanism

BACKGROUND: Mutations in key tumor suppressor genes such as tumor protein 53 (TP53) and phosphatase and tensin homolog deleted on chromosome ten (PTEN) are the main genetic alterations in cancers. TP53 mutations have been found in most patients with non-small cell lung cancer (NSCLC), whereas PTEN m...

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Detalhes bibliográficos
Main Authors: Li, Gang, Zhao, Jingfeng, Peng, Xianjing, Liang, Jian, Deng, Xin, Chen, Yuxiang
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3353764/
https://ncbi.nlm.nih.gov/pubmed/22489661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cbr.2011.1154
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