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Active cell movements coupled to positional induction are involved in lineage segregation in the mouse blastocyst

In the mouse blastocyst, some cells of the inner cell mass (ICM) develop into primitive endoderm (PE) at the surface, while deeper cells form the epiblast. It remained unclear whether the position of cells determines their fate, such that gene expression is adjusted to cell position, or if cells are...

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Detalhes bibliográficos
Main Authors: Meilhac, Sigolène M., Adams, Richard J., Morris, Samantha A., Danckaert, Anne, Le Garrec, Jean-François, Zernicka-Goetz, Magdalena
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3353123/
https://ncbi.nlm.nih.gov/pubmed/19422818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2009.04.036
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