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Bio-inspired synthesis and biological evaluation of a colchicine-related compound library
A bio-inspired investigation of the reactions of substrates of type 1 with VOF(3) and PIFA [phenyliodine(III) bis(trifluoroacetate)] led to a collection of colchicine-like compounds 2–5 and related systems. Biological evaluation revealed that some of the synthesized products had significant cytotoxi...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3353021/ https://ncbi.nlm.nih.gov/pubmed/22542017 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2012.04.007 |
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