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α-Synuclein Genetic Variants Predict Faster Motor Symptom Progression in Idiopathic Parkinson Disease

Currently, there are no reported genetic predictors of motor symptom progression in Parkinson’s disease (PD). In familial PD, disease severity is associated with higher α-synuclein (SNCA) expression levels, and in postmortem studies expression varies with SNCA genetic variants. Furthermore, SNCA is...

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Detalhes bibliográficos
Main Authors: Ritz, Beate, Rhodes, Shannon L., Bordelon, Yvette, Bronstein, Jeff
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3352914/
https://ncbi.nlm.nih.gov/pubmed/22615757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036199
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