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α-Synuclein Genetic Variants Predict Faster Motor Symptom Progression in Idiopathic Parkinson Disease

Currently, there are no reported genetic predictors of motor symptom progression in Parkinson’s disease (PD). In familial PD, disease severity is associated with higher α-synuclein (SNCA) expression levels, and in postmortem studies expression varies with SNCA genetic variants. Furthermore, SNCA is...

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Bibliografische gegevens
Hoofdauteurs: Ritz, Beate, Rhodes, Shannon L., Bordelon, Yvette, Bronstein, Jeff
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2012
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3352914/
https://ncbi.nlm.nih.gov/pubmed/22615757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036199
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