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α-Synuclein Genetic Variants Predict Faster Motor Symptom Progression in Idiopathic Parkinson Disease

Currently, there are no reported genetic predictors of motor symptom progression in Parkinson’s disease (PD). In familial PD, disease severity is associated with higher α-synuclein (SNCA) expression levels, and in postmortem studies expression varies with SNCA genetic variants. Furthermore, SNCA is...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ritz, Beate, Rhodes, Shannon L., Bordelon, Yvette, Bronstein, Jeff
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3352914/
https://ncbi.nlm.nih.gov/pubmed/22615757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036199
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