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α-Synuclein Genetic Variants Predict Faster Motor Symptom Progression in Idiopathic Parkinson Disease

Currently, there are no reported genetic predictors of motor symptom progression in Parkinson’s disease (PD). In familial PD, disease severity is associated with higher α-synuclein (SNCA) expression levels, and in postmortem studies expression varies with SNCA genetic variants. Furthermore, SNCA is...

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Autors principals: Ritz, Beate, Rhodes, Shannon L., Bordelon, Yvette, Bronstein, Jeff
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3352914/
https://ncbi.nlm.nih.gov/pubmed/22615757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036199
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