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JC virus promoter/enhancers contain TATA box-associated Spi-B-binding sites that support early viral gene expression in primary astrocytes

JC virus (JCV) is the aetiological agent of the demyelinating disease progressive multifocal leukoencephalopathy, an AIDS defining illness and serious complication of mAb therapies. Initial infection probably occurs in childhood. In the working model of dissemination, virus persists in the kidney an...

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Detalhes bibliográficos
Main Authors: Marshall, Leslie J., Moore, Lisa D., Mirsky, Matthew M., Major, Eugene O.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for General Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3352355/
https://ncbi.nlm.nih.gov/pubmed/22071512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/vir.0.035832-0
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