Detection of JC Virus DNA in Human Tonsil Tissue: Evidence for Site of Initial Viral Infection

Progressive multifocal leukoencephalopathy is a demyelinating disease of the human central nervous system that results from lytic infection of oligodendrocytes by the polyomavirus JC (JCV). Originally, JCV was thought to replicate exclusively in human glial cells, specifically oligodendrocytes. Howe...

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Bibliographic Details
Main Authors: Monaco, Maria Chiara G., Jensen, Peter N., Hou, Jean, Durham, Linda C., Major, Eugene O.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1998
Subjects:
Viral Pathogenesis and Immunity
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC110504/
https://ncbi.nlm.nih.gov/pubmed/9811728
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