Miglustat Improves Purkinje Cell Survival and Alters Microglial Phenotype in Feline Niemann-Pick Disease Type C

Niemann-Pick disease type C (NPC disease) is an incurable cellular lipid trafficking disorder characterized by neurodegeneration and intralysosomal accumulation of cholesterol and glycosphingolipids. Treatment with miglustat, a small imino sugar that reversibly inhibits glucosylceramide synthase, wh...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Stein, Veronika M., Crooks, Alexandra, Ding, Wenge, Prociuk, Maria, O’Donnell, Patricia, Bryan, Caroline, Sikora, Tracey, Dingemanse, Jasper, Vanier, Marie T., Walkley, Steven U., Vite, Charles H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3352323/
https://ncbi.nlm.nih.gov/pubmed/22487861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/NEN.0b013e31825414a6
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados