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Mycobacterium tuberculosis thymidylate synthase gene thyX is essential and potentially bifunctional, while thyA deletion confers resistance to p-aminosalicylic acid

Thymidylate synthase (TS) enzymes catalyse the biosynthesis of deoxythymidine monophosphate (dTMP or thymidylate), and so are important for DNA replication and repair. Two different types of TS proteins have been described (ThyA and ThyX), which have different enzymic mechanisms and unrelated struct...

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Detaylı Bibliyografya
Asıl Yazarlar: Fivian-Hughes, Amanda S., Houghton, Joanna, Davis, Elaine O.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Society for General Microbiology 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3352284/
https://ncbi.nlm.nih.gov/pubmed/22034487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/mic.0.053983-0
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