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Dihydrotestosterone Ameliorates Degeneration in Muscle, Axons and Motoneurons and Improves Motor Function in Amyotrophic Lateral Sclerosis Model Mice

Amyotrophic lateral sclerosis (ALS) is a lethal disease characterized by a progressive loss of motoneurons. The clinical symptoms include skeletal muscle weakness and atrophy, which impairs motor performance and eventually leads to respiratory failure. We tested whether dihydrotestosterone (DHT), wh...

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Detalhes bibliográficos
Main Authors: Yoo, Young-Eun, Ko, Chien-Ping
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3351454/
https://ncbi.nlm.nih.gov/pubmed/22606355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037258
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