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Axonal Dysfunction Precedes Motor Neuronal Death in Amyotrophic Lateral Sclerosis
Wide-spread fasciculations are a characteristic feature in amyotrophic lateral sclerosis (ALS), suggesting motor axonal hyperexcitability. Previous excitability studies have shown increased nodal persistent sodium conductances and decreased potassium currents in motor axons of ALS patients, both of...
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| Publicado no: | PLoS One |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4934877/ https://ncbi.nlm.nih.gov/pubmed/27383069 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0158596 |
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