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Dysregulated axonal RNA translation in amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis (ALS) is an adult‐onset motor neuron disease that has been associated with a diverse array of genetic changes. Prominent among these are mutations in RNA‐binding proteins (RBPs) or repeat expansions that give rise to toxic RNA species. RBPs are additionally central comp...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Wiley Interdiscip Rev RNA
Hauptverfasser: Yasuda, Kyota, Mili, Stavroula
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley & Sons, Inc. 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5071740/
https://ncbi.nlm.nih.gov/pubmed/27038103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/wrna.1352
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