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Dysregulated axonal RNA translation in amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis (ALS) is an adult‐onset motor neuron disease that has been associated with a diverse array of genetic changes. Prominent among these are mutations in RNA‐binding proteins (RBPs) or repeat expansions that give rise to toxic RNA species. RBPs are additionally central comp...

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Detalhes bibliográficos
Publicado no:Wiley Interdiscip Rev RNA
Main Authors: Yasuda, Kyota, Mili, Stavroula
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5071740/
https://ncbi.nlm.nih.gov/pubmed/27038103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/wrna.1352
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