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Transgenic Expression of Nonclassically Secreted FGF Suppresses Kidney Repair

FGF1 is a signal peptide-less nonclassically released growth factor that is involved in angiogenesis, tissue repair, inflammation, and carcinogenesis. The effects of nonclassical FGF export in vivo are not sufficiently studied. We produced transgenic mice expressing FGF1 in endothelial cells (EC), w...

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Dettagli Bibliografici
Autori principali: Kirov, Aleksandr, Duarte, Maria, Guay, Justin, Karolak, Michele, Yan, Cong, Oxburgh, Leif, Prudovsky, Igor
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3351418/
https://ncbi.nlm.nih.gov/pubmed/22606265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036485
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