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Transgenic Expression of Nonclassically Secreted FGF Suppresses Kidney Repair

FGF1 is a signal peptide-less nonclassically released growth factor that is involved in angiogenesis, tissue repair, inflammation, and carcinogenesis. The effects of nonclassical FGF export in vivo are not sufficiently studied. We produced transgenic mice expressing FGF1 in endothelial cells (EC), w...

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Detalhes bibliográficos
Main Authors: Kirov, Aleksandr, Duarte, Maria, Guay, Justin, Karolak, Michele, Yan, Cong, Oxburgh, Leif, Prudovsky, Igor
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3351418/
https://ncbi.nlm.nih.gov/pubmed/22606265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036485
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