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Phosphatidylserine externalization and membrane blebbing are involved in the nonclassical export of FGF1

The mechanisms of nonclassical export of signal peptide-less proteins remain insufficiently understood. Here we demonstrate that stress-induced unconventional export of FGF1, a potent and ubiquitously expressed mitogenic and proangiogenic protein, is associated with and dependent on the formation of...

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Detalhes bibliográficos
Main Authors: Kirov, Aleksandr, Al-Hashimi, Huda, Solomon, Phil, Mazur, Courtney, Thorpe, Philip E., Sims, Peter J., Tarantini, Francesca, Suresh Kumar, Thallapuranam K., Prudovsky, Igor
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3264788/
https://ncbi.nlm.nih.gov/pubmed/22034063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.23425
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