Antiviral activity and possible mechanisms of action of oligonucleotides-poly(L-lysine) conjugates targeted to vesicular stomatitis virus mRNA and genomic RNA.

Synthetic oligonucleotides (oligomers) complementary to vesicular stomatitis virus (VSV) N protein mRNA have specific antiviral properties at concentrations lower than 1 microM when they are covalently linked to poly(L-lysine) (PLL). Since it is generally postulated that antisense oligomers act at t...

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Pubblicato in:	Nucleic Acids Res
Autori principali:	Degols, G, Leonetti, J P, Gagnor, C, Lemaitre, M, Lebleu, B
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Oxford University Press 1989
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC335136/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2479915/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/17.22.9341
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