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Antibody-targeted liposomes containing oligodeoxyribonucleotides complementary to viral RNA selectively inhibit viral replication.

Mouse L929 cells were incubated with antibody-targeted liposomes containing oligodeoxyribonucleotides (oligomers). When the oligomer was a 15-mer complementary to the 5'-end region of the mRNA encoding the N protein of vesicular stomatitis virus, the cells became less permissive for multiplication o...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Leonetti, J P, Machy, P, Degols, G, Lebleu, B, Leserman, L
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1990
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC53706/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2157200/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.7.2448
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