ADP-ribosylhydrolase 3 (ARH3), Not Poly(ADP-ribose) Glycohydrolase (PARG) Isoforms, Is Responsible for Degradation of Mitochondrial Matrix-associated Poly(ADP-ribose)

Important cellular processes are regulated by poly(ADP-ribosyl)ation. This protein modification is catalyzed mainly by nuclear poly(ADP-ribose) polymerase (PARP) 1 in response to DNA damage. Cytosolic PARP isoforms have been described, whereas the presence of poly(ADP-ribose) (PAR) metabolism in mit...

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Autores principales: Niere, Marc, Mashimo, Masato, Agledal, Line, Dölle, Christian, Kasamatsu, Atsushi, Kato, Jiro, Moss, Joel, Ziegler, Mathias
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2012
Materias:
Cell Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3351285/
https://ncbi.nlm.nih.gov/pubmed/22433848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.349183
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