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Membrane-bound Trafficking Regulates Nuclear Transport of Integral Epidermal Growth Factor Receptor (EGFR) and ErbB-2

Nuclear localization of multiple receptor-tyrosine kinases (RTKs), such as EGF receptor (EGFR), ErbB-2, FGF receptor (FGFR), and many others, has been reported by several groups. We previously showed that cell surface EGFR is trafficked to the nucleus through a retrograde pathway from the Golgi to t...

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Detalhes bibliográficos
Main Authors: Wang, Ying-Nai, Lee, Heng-Huan, Lee, Hong-Jen, Du, Yi, Yamaguchi, Hirohito, Hung, Mien-Chie
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3351284/
https://ncbi.nlm.nih.gov/pubmed/22451678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.314799
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